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Category Health, Video | Permalink | 1. February 2007

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Sickle cell disease is a disorder of the blood and, consequently, the circulatory system. Sickle cell affects what is known as hemoglobin in the red blood cell. Hemoglobin’s function is to carry oxygen within the cell and transport to where it is needed. But in an affected sickle cell, the red blood cell is misshapen, appearing in a crescent moon or sickle shape. A normal red blood cell is pliant and round, which enables it to easily flow through the bloodstream, whereas a sickle cell is rigid and, due to its shape, causes a clot to form in a blood vessel.

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Sickle cell disease develops in a person when he or she receives the sickle cell trait from their mother and father. If a person only receives the trait from one parent, the child merely becomes a carrier of the affliction. Usually, there are enough normal red blood cells in the body to carry oxygen from the lungs to the places where it is used. On the other hand, if a child receives the trait from both parents, they develop sickle cell anemia. This disease can adversely affect the internal organs and can even cause death.

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